Ranking the Risk of Animal-to-Human Spillover for Newly Discovered Viruses
The death toll and economic loss resulting from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic are stark reminders that we are vulnerable to zoonotic viral threats. Strategies are needed to identify and characterize animal viruses that pose the greatest risk of spillover and spread in humans and inform public health interventions. Using expert opinion and scientific evidence, we identified host, viral, and environmental risk factors contributing to zoonotic virus spillover and spread in humans. We then developed a risk ranking framework and interactive web tool, SpillOver, that estimates a risk score for wildlife-origin viruses, creating a comparative risk assessment of viruses with uncharacterized zoonotic spillover potential alongside those already known to be zoonotic.
https://biodiversitylinks.org/learning-evidence/one-health-evidence/one-health-evidence-inbox/grange-2021_ranking-the-risk-of-animal-to-human-spillover-for-newly-discovered-viruses.pdf/view
https://biodiversitylinks.org/learning-evidence/one-health-evidence/one-health-evidence-inbox/grange-2021_ranking-the-risk-of-animal-to-human-spillover-for-newly-discovered-viruses.pdf/@@download/image/image.png
File
Ranking the Risk of Animal-to-Human Spillover for Newly Discovered Viruses
Author(s):
Zoë L. Grangea
,
Tracey Goldsteina
,
Christine K. Johnsona
,
Simon Anthony
,
Kirsten Gilardia
,
Peter Daszakb
,
Kevin J. Olival
,
Tammie O’Rourke
,
Suzan Murray
,
Sarah H. Olsong
,
Eri Togamia
,
Gema Vidala
,
Expert Panel
,
PREDICT Consortium
,
Jonna A. K. Mazeta
Publication Date: 2021
DOWNLOAD FILE
The death toll and economic loss resulting from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic are stark reminders that we are vulnerable to zoonotic viral threats. Strategies are needed to identify and characterize animal viruses that pose the greatest risk of spillover and spread in humans and inform public health interventions. Using expert opinion and scientific evidence, we identified host, viral, and environmental risk factors contributing to zoonotic virus spillover and spread in humans. We then developed a risk ranking framework and interactive web tool, SpillOver, that estimates a risk score for wildlife-origin viruses, creating a comparative risk assessment of viruses with uncharacterized zoonotic spillover potential alongside those already known to be zoonotic.
