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Drivers of Antibiotic Resistance Transmission in Low-and Middle-Income Countries from a One Health Perspective - A Review

Drivers of Antibiotic Resistance Transmission in Low-and Middle-Income Countries from a One Health Perspective - A Review

Author(s): Katia Iskandar , Laurent Molinier , Souheil Hallit , Massimo Sartelli , Fausto Catena , Federico Coccolini , Timothy Craig Hardcastle , Christine Roques , Pascale Salameh

Publication Date: 2020

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Antibiotic resistance is an ecosystem problem threatening the interrelated human-animal-environment health under the “One Health” framework. Resistant bacteria arising in one geographical area can spread via cross-reservoir transmission to other areas worldwide either by direct exposure or through the food chain and the environment. Drivers of antibiotic resistance are complex and multi-sectoral, particularly in Lower- and Middle-income countries. These include inappropriate socio-ecological behaviors; poverty; overcrowding; lack of surveillance systems; food supply chain safety issues; highly contaminated waste effluents; and loose rules and regulations.

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