Biologically diverse ecosystems play important roles in promoting health and fighting disease by providing goods and services, including wild foods, natural medicines, and clean air and water. Human health also plays an important role in biodiversity outcomes, as poor health and low access to health services are drivers of biodiversity loss. Ecosystems, including intact forests, also help regulate common infectious diseases, like malaria, by inhibiting conditions that spread disease vectors. The COVID-19 pandemic has brought into stark reality the connections between wildlife, the environment, public health, and human security. Biodiversity conservation and sound management of natural resources improve ecosystem function and productivity, with positive outcomes for human health and well-being.